Document Detail

Transthoracic defibrillation: effect of dual-pathway sequential pulse shocks and single-pathway biphasic pulse shocks in a canine model.
MedLine Citation:
PMID:  8417549     Owner:  NLM     Status:  MEDLINE    
To determine whether dual-pathway sequential shocks and single-pathway biphasic shocks improved the efficacy of transthoracic defibrillation, we delivered single or sequential truncated waveform shocks of variable duration, voltage, and direction (polarity) to three groups of closed-chest dogs. Dual-pathway sequential shocks were assessed in group 1 (eight animals), biphasic shocks with a single pathway were compared in 11 dogs (group 2), and the effect of varying the duration of the biphasic shocks was assessed in group 3 (four animals). There was no improvement in success rates of the intervention shocks compared with a standard single "control" shock at any energy level. In this experimental model unidirectional or biphasic sequential shocks given over single or dual pathways were not superior to standard single-pulse transthoracic defibrillation.
B D Scott; M J Kallok; C Birkett; R A Kieso; R E Kerber
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American heart journal     Volume:  125     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-01-26     Completed Date:  1993-01-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  99-109     Citation Subset:  AIM; IM    
Cardiovascular Center, University of Iowa College of Medicine, Iowa City.
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MeSH Terms
Analysis of Variance
Disease Models, Animal*
Electric Countershock / instrumentation,  methods*,  statistics & numerical data
Evaluation Studies as Topic
Remission Induction
Ventricular Fibrillation / epidemiology,  therapy*
Grant Support

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