| Transthoracic Doppler echocardiography of mammary artery grafts to assess graft function. | |
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MedLine Citation:
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PMID: 15685302 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Transthoracic Doppler echocardiography of internal mammary artery grafts (MAGs) has been tested by the supraclavicular approach, but little information is available about the parasternal approach. OBJECTIVE: To evaluate the usefulness of parasternal transthoracic Doppler echocardiography to assess the patency of left and right MAGs. PATIENTS AND METHODS: Forty-eight patients with previous MAGs were divided into two groups on the basis of coronary angiography: 42 patients had patent MAGs and six patients had severe MAG stenosis. Doppler echocardiography of MAGs was performed on all patients, both at baseline and after low-dose dipyridamole infusion. Systolic and diastolic time-velocity integrals and their ratios were obtained, and MAG flow reserve was calculated. RESULTS: Patients with patent MAGs had a predominant diastolic flow, while a prominent systolic pattern was found in the presence of MAG stenosis. In patients with stenosis, baseline Doppler analysis showed a lower diastolic peak velocity (DPV) (P<0.01), diastolic time-velocity integral (P<0.05), and diastolic and systolic time-velocity integral ratios (both P<0.005), and a reduced MAG flow reserve (P<0.001). In the overall population, when adjusting for clinical variables, a multilinear regression analyis underscored MAG flow reserve (beta=0.38, P<0.01) and baseline DPV (beta=0.29, P<0.05) as independent determinants of MAG stenosis (cumulative R2=0.25, P<0.005). CONCLUSIONS: Doppler echocardiographic evaluation of MAGs is a reliable, noninvasive tool to assess MAG patency and functional status of the vessel. MAG blood flow reserve and baseline DPV are independent determinants of MAG stenosis. |
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Authors:
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Silvana Cicala; Attilio Renzulli; Maurizio Galderisi; Luigi De Simone; Marisa De Feo; Francesco Onorati; Flavio Cerasuolo; Giulio Bonzani; Pio Caso; Maurizio Cotrufo |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Canadian journal of cardiology Volume: 21 ISSN: 0828-282X ISO Abbreviation: Can J Cardiol Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-02-01 Completed Date: 2005-03-31 Revised Date: 2008-04-09 |
Medline Journal Info:
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Nlm Unique ID: 8510280 Medline TA: Can J Cardiol Country: Canada |
Other Details:
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Languages: eng Pagination: 45-9 Citation Subset: IM |
Affiliation:
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Department of Cardiothoracic and Respiratory Sciences, Second University of Naples, Monaldi Hospital, Naples, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cohort Studies Coronary Artery Bypass / adverse effects, methods* Coronary Disease / surgery*, ultrasonography* Echocardiography, Doppler, Color Echocardiography, Transesophageal* Female Graft Rejection Graft Survival Humans Internal Mammary-Coronary Artery Anastomosis Linear Models Male Middle Aged Monitoring, Physiologic / methods Postoperative Complications / ultrasonography Probability Prognosis Risk Assessment Sensitivity and Specificity Statistics, Nonparametric Vascular Patency |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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