| Transrectal ultrasound-guided transperineal botulinum toxin a injection to the external urethral sphincter for treatment of detrusor external sphincter dyssynergia in patients with spinal cord injury. | |
| | |
MedLine Citation:
|
PMID: 20298821 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To evaluate the effects of a single transrectal ultrasound (TRUS)-guided transperineal injection of botulinum toxin A (BTX-A) to the external urethral sphincter (EUS) for treating detrusor external sphincter dyssynergia (DESD). DESIGN: Descriptive study. SETTING: Rehabilitation hospital affiliated with a medical university. PARTICIPANTS: Patients (N=18) with suprasacral spinal cord injury who had DESD confirmed on video-urodynamic study. INTERVENTIONS: A single dose of 100U BTX-A was applied into the EUS via TRUS-guided transperineal route injection. MAIN OUTCOME MEASURES: Maximal detrusor pressure, detrusor leak-point pressure, integrated electromyography (iEMG), maximal pressure on static urethral pressure profilometry, and postvoiding residuals. RESULTS: There were significant reductions in iEMG (P=.008) and static (P=.012) and dynamic urethral pressure (P=.023), but not in detrusor pressure and detrusor leak-point pressure after treatment. Postvoiding residuals also significantly decreased in the first and second month after treatment (P<.012). CONCLUSIONS: TRUS-guided transperineal injection of BTX-A has beneficial effects in treating DESD. |
| | |
Authors:
|
Sung-Lang Chen; Liu-Ing Bih; Gin-Den Chen; Yu-Hui Huang; Ya-Hui You; Henry L Lew |
Publication Detail:
|
Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Archives of physical medicine and rehabilitation Volume: 91 ISSN: 1532-821X ISO Abbreviation: Arch Phys Med Rehabil Publication Date: 2010 Mar |
Date Detail:
|
Created Date: 2010-03-19 Completed Date: 2010-04-01 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 2985158R Medline TA: Arch Phys Med Rehabil Country: United States |
Other Details:
|
Languages: eng Pagination: 340-4 Citation Subset: AIM; IM |
Copyright Information:
|
Copyright 2010 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Urology, Chung Shan Medical University Hospital, School of Medicine, Chung Shan Medical University, Taichung, Taiwan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Autonomic Dysreflexia / diagnosis, etiology, rehabilitation* Botulinum Toxins / administration & dosage* Cervical Vertebrae Electromyography Humans Injections, Intramuscular Male Thoracic Vertebrae Urethra / physiopathology, ultrasonography Urethral Stricture / diagnosis, etiology, rehabilitation* Urinary Retention / etiology, prevention & control Urinary Tract Infections / etiology, prevention & control Urodynamics |
| Chemical | |
Reg. No./Substance:
|
0/Botulinum Toxins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Efficacy of Partial Body Weight-Supported Treadmill Training Compared With Overground Walking Practi...
Next Document: Utility of Functional Status for Classifying Community Versus Institutional Discharges After Inpatie...