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The Transrectal Ultrasonography of Prostate in Men with Congenital Hypogonadism Treated by Long Term Testosterone Replacement Therapy.
MedLine Citation:
PMID:  23101893     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: The aim of the study was to evaluate prostate transrectal ultrasonography findings in men with congenital hypogonadism treated by long term testosterone replacement therapy.Methods: We have gradually included 31 men with congenital hypogonadism in period of 2001-2011. The average follow-up was 7.3 years (2 months - 10.8 years). We have used Sustanon® 250 i.m. every 3 weeks or Nebido® i.m. every 3 months for continual testosterone replacement therapy. We performed to all patients the transrectal ultrasonography of prostate and seminal vesicles by biplanar rectal probe every 6 months. Results: During the transrectal ultrasonography we observed in 22 (71.0 %) patients changes in prostatic tissue. In case of 12 patients were diagnosed asymptomatic prostatic cysts, in 9 patients prostatolithiasis and in 5 patients changes in echogenity of prostatic tissue. In 2 patients was found simultaneous occurrence of prostatic cyst and prostolithiasis, in further 2 patients simultaneous occurrence of hyperechogenic prostatic lesion and prostatolithiasis. The above described findings were diagnosed in 5 patients in the treatment lasting from 3 to 5 years, for the other 17 men with hormone replacement therapy longer than 5 years.Conclusions: The study presents long term results of complex treatment in patients with disorders of sexual development, onset and progress of puberty. The long term treatment of these patients in interdisciplinary cooperation of endocrinologist and andrologist may significantly contribute to clarify an impact of testosterone replacement therapy on prostate development. Key words: hypogonadism, hormonal replacement therapy, testosterone, transrectal ultrasonography, prostatic cyst, prostatolithiasis, prostate cancer, follow up.
Authors:
Jiří Heráček; Karim El Balouly; Vladimír Sobotka; Marta Snajderova; Bozena Kalvachova; Michael Urban
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Casopis lekaru ceskych     Volume:  151     ISSN:  0008-7335     ISO Abbreviation:  Cas. Lek. Cesk.     Publication Date:  2012  
Date Detail:
Created Date:  2012-10-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0004743     Medline TA:  Cas Lek Cesk     Country:  -    
Other Details:
Languages:  ENG     Pagination:  392-396     Citation Subset:  -    
Vernacular Title:
Transrektální sonografie prostaty u mužů s vrozeným hypogonadismem léčeným dlouhodobou substituční terapií testosteronem.
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