Document Detail

Transpupillary thermotherapy in subfoveal choroidal neovascular membrane secondary to age-related macular degeneration.
MedLine Citation:
PMID:  15132377     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To report our initial experience in the treatment of subfoveal choroidal neovascular membrane, secondary to age-related macular degeneration (AMD) by transpupillary thermotherapy (TTT). METHODS: Fifty consecutive patients with subfoveal choroidal neovascularisation (CNV) secondary to AMD, were included in the study. The parameters assessed before the TTT were visual acuity by ETDRS chart, scotoma score by Amsler grid chart, reading speed, fundus examination by direct and indirect ophthalmoscope as well as +90 Diopter lens followed by digital fundus photography and fluorescein angiography (FA). RESULTS: The letter visual acuity improved or stabilized in 72% cases up to 12 weeks after TTT. Mean scotoma score decreased from a mean of 47.56, to 43.56 at 6 weeks and to 37 at 12 weeks. Mean reading speed increased from 27.04 words/minute at pretreatment to 34.52 words/minute at 6 weeks and 37.33 words/minute 12 weeks after TTT. CONCLUSION: TTT is not only a cheaper alternative to photodynamic therapy (PDT), but also is an efficacious tool in stabilisation or improvement of visual acuity in the management of subfoveal choroidal neovascular membrane due to AMD.
Lalit Verma; Hem K Tewari; Sanjeev Nainiwal; Jayaram Ravindranathan
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Indian journal of ophthalmology     Volume:  52     ISSN:  0301-4738     ISO Abbreviation:  Indian J Ophthalmol     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-05-10     Completed Date:  2004-06-14     Revised Date:  2008-09-03    
Medline Journal Info:
Nlm Unique ID:  0405376     Medline TA:  Indian J Ophthalmol     Country:  India    
Other Details:
Languages:  eng     Pagination:  35-40     Citation Subset:  IM    
Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
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MeSH Terms
Aged, 80 and over
Choroidal Neovascularization / etiology,  therapy*
Fluorescein Angiography
Follow-Up Studies
Hyperthermia, Induced / methods*
Macular Degeneration / complications,  therapy*
Middle Aged
Treatment Outcome
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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