Document Detail


Transport of free and conjugated steroids from the boar testis in lymph, venous blood and rete testis fluid.
MedLine Citation:
PMID:  6296258     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 12 anaesthetized boars the concentrations of oestrone sulphate and dehydroepiandrosterone sulphate (DHAS) were 15- to 35-fold higher in lymph collected from a vessel in the spermatic cord than in testicular venous blood plasma from a vein in the spermatic cord. The concentrations of testosterone, total unconjugated oestrogens and dehydroepiandrosterone (DHA) were about twofold higher in lymph. The concentrations of all steroids studied were higher in testicular venous blood plasma than in arterial blood plasma (testosterone about sixfold; total unconjugated oestrogens about fourfold; oestrone sulphate about threefold; DHA and DHAS about twofold), but the concentrations of testosterone, total unconjugated oestrogens and oestrone sulphate in rete testis fluid were comparable to those in arterial blood plasma. Lymph flow from the pig testis was about 7% of plasma flow so that about 80% of the oestrone sulphate and DHAS produced by the testis leaves the organ in the lymph; the comparable values for testosterone, total unconjugated oestrogen and DHA were about 20%. In the 90-min period following an injection of human chorionic gonadotrophin there were substantial increases in the concentration of testosterone and smaller increases in the other steroids in arterial and spermatic venous blood plasma and in testicular lymph, but not in rete testis fluid; there were also small increases in lymph flow, but no change in blood flow.
Authors:
B P Setchell; M S Laurie; A P Flint; R B Heap
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of endocrinology     Volume:  96     ISSN:  0022-0795     ISO Abbreviation:  J. Endocrinol.     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-03-17     Completed Date:  1983-03-17     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0375363     Medline TA:  J Endocrinol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  127-36     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Androgens / metabolism*
Animals
Biological Transport, Active
Body Fluids / metabolism
Dehydroepiandrosterone / analogs & derivatives,  metabolism
Dehydroepiandrosterone Sulfate
Estrogens / metabolism*
Estrogens, Conjugated (USP) / metabolism
Estrone / analogs & derivatives,  metabolism
Lymph / metabolism*
Male
Rete Testis / metabolism
Swine
Testis / metabolism*
Testosterone / metabolism
Chemical
Reg. No./Substance:
0/Androgens; 0/Estrogens; 0/Estrogens, Conjugated (USP); 481-97-0/estrone sulfate; 53-16-7/Estrone; 53-43-0/Dehydroepiandrosterone; 58-22-0/Testosterone; 651-48-9/Dehydroepiandrosterone Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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