Document Detail


Transport calculations of the influence of physical factors on depth-dose distributions in boron neutron capture therapy.
MedLine Citation:
PMID:  2117293     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Distributions of thermal neutron fluence and capture gamma ray absorbed dose rates were evaluated, taking into consideration various physical factors relevant to boron neutron capture therapy. The use of a larger neutron irradiation aperture was associated with an increase in thermal neutron fluence and capture gamma ray absorbed dose rates. Radiation leakage was more significant with smaller phantoms. Attenuation of thermal neutron fluence rates by 10B suggested that there was an optimal 10B concentration (less than 100 PPM) for a given tumour. Deuteration of water allowed better penetration of thermal neutrons with less capture gamma rays and is potentially applicable for the treatment of deep-seated brain tumours.
Authors:
T Matsumoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physics in medicine and biology     Volume:  35     ISSN:  0031-9155     ISO Abbreviation:  Phys Med Biol     Publication Date:  1990 Jul 
Date Detail:
Created Date:  1990-09-20     Completed Date:  1990-09-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401220     Medline TA:  Phys Med Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  971-8     Citation Subset:  IM    
Affiliation:
Atomic Energy Research Laboratory, Musashi Institute of Technology, Kawasaki-shi, Japan.
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MeSH Terms
Descriptor/Qualifier:
Boron*
Humans
Isotopes
Models, Biological
Models, Structural
Neoplasms / radiotherapy*
Neutrons*
Radiotherapy Dosage
Radiotherapy, High-Energy
Chemical
Reg. No./Substance:
0/Isotopes; 7440-42-8/Boron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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