Document Detail


Transplantation of the reversed dermis from skin leading to repair of the buccal mucosal epithelium.
MedLine Citation:
PMID:  6749887     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Skin grafting or mucosal grafting has been widely applied as the established method to compensate mucosal defects. However, in the grafted skin the epidermis never transformed into the mucosal epithelium; the original nature of the transplant was maintained as skin. The available donor of mucosa is also strictly limited. Therefore, an improvement in method has been much needed in the field of oral surgery. We tried to transplant the dermis freed completely from the epidermis instead of the full-thickness skin, and succeeded in compensation of the mucosal defect. The defects of the buccal mucosa in 30 dogs were repaired, one side with reversed dermis graft (RDG) in which the dermis was turned inside out and sutured onto the bed. On the other side, the ordinary free full-thickness skin graft (FTSG) was carried out as a control. Comparative clinical and histological observations were conducted to analyze the healing processes. In RDG the graft was covered by the surrounding mucosal epithelium to form the mucosal tissue, while the implanted tissue inhibited the wound constricture. Histological examination revealed that the epithelial elements underwent degeneration, presumably through being embedded by the grafting of the dermis inside out. The epithelium covering the dermis graft seems to be nothing but normal oral mucosal epithelium.
Authors:
M Ueda; O Yamada; S Torii; T Oka; G Eguchi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of craniofacial genetics and developmental biology     Volume:  1     ISSN:  0270-4145     ISO Abbreviation:  J. Craniofac. Genet. Dev. Biol.     Publication Date:  1982  
Date Detail:
Created Date:  1982-12-02     Completed Date:  1982-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8109845     Medline TA:  J Craniofac Genet Dev Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  391-400     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cheek
Dogs
Epithelium
Mouth Mucosa / surgery*,  ultrastructure
Skin Transplantation*
Wound Healing

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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