| Transplantation for primary biliary cirrhosis. | |
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MedLine Citation:
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PMID: 9170201 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Primary biliary cirrhosis (PBC) remains one of the commoner indications for orthotopic liver replacement. The two main indications for transplantation are poor quality of life (because of the liver) or end-stage liver disease. A number of prognostic models have identified risk factors indicating poor prognosis, but in practice serum bilirubin greater than 150 mumol/L is used most commonly. Other indications for transplantation include progression of hepatopulmonary syndrome, increasing osteoporosis, evidence of malnutrition, and development of hepatocellular carcinoma. Postoperatively, patients do well. Recurrence of PBC remains controversial, but an increasing number of centers now report that a proportion of patients develop evidence of recurrent disease in the allograft. As yet PBC recurrence remains of little practical importance, although as survival increases beyond 10 years, this may become more relevant. |
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Authors:
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J Neuberger |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Seminars in liver disease Volume: 17 ISSN: 0272-8087 ISO Abbreviation: Semin. Liver Dis. Publication Date: 1997 May |
Date Detail:
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Created Date: 1997-08-25 Completed Date: 1997-08-25 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8110297 Medline TA: Semin Liver Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 137-46 Citation Subset: IM |
Affiliation:
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Queen Elizabeth Hospital, Edgbaston, Birmingham, England. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Fatigue
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etiology Humans Liver Cirrhosis, Biliary / complications, mortality, therapy* Liver Transplantation* Patient Selection Predictive Value of Tests Prognosis Pruritus / etiology Quality of Life Recurrence Survival Rate Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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