| TRANSPLANTATION IMMUNITY OF GESTATIONAL ORIGIN IN INFANT RATS. | |
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MedLine Citation:
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PMID: 14237209 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Comparison of the survival times of homografts of BN skin on 3-day-old Lewis rats born of mothers of the same isogenic strain with those of BN grafts on infant Lewis hosts that had developed in an F(1) (Lewis x BN) hybrid, gave no evidence of maternally induced tolerance as a result of development in an antigenically alien environment. On the contrary, the significantly shorter median survival time of the grafts on the hybrid-derived Lewis group suggests that sensitization had occurred as a consequence of natural exposure during gestation to small numbers of maternal cells. |
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Authors:
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R E BILLINGHAM; J PALM; W K SILVERS |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 147 ISSN: 0036-8075 ISO Abbreviation: Science Publication Date: 1965 Jan |
Date Detail:
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Created Date: 1965-04-01 Completed Date: 1996-12-01 Revised Date: 2011-11-30 |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 514-6 Citation Subset: OM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals, Newborn* Immune Tolerance* Maternal-Fetal Exchange* Pregnancy* Pregnancy, Animal* Rats* Research* Skin Transplantation* Transplantation Immunology* Transplantation, Homologous* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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