Document Detail


Transplacental transfer of Legionella pneumophila antibodies.
MedLine Citation:
PMID:  3696826     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to determine the extent to which Legionella pneumophila antibodies are passively transferred transplacentally into the fetal circulation, 199 matched serums of mothers and their newborn infants were tested using the indirect fluorescent polyclonal antibody technique. Considering L. pneumophila antibody titers of greater than or equal to 1:64 as evidence of inapparent infection, the overall prevalence rate was 35.7% for the mothers and 14.1% for their newborns. Among the mothers who were seropositive at greater than or equal to 1:64, 36.6% of their matched infants acquired antibodies transplacentally. With only two exceptions there were no newborns with an antibody titer greater than or equal to 1:64 whose mothers did not also evidence at least the same titer.
Authors:
S L Silberg; C H Lawrence; P J Guthrie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  6     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1988-01-27     Completed Date:  1988-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  925-7     Citation Subset:  IM    
Affiliation:
Department of Biostatistics and Epidemiology, University of Oklahoma, Oklahoma City 73190.
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Bacterial / analysis*
Female
Humans
Infant, Newborn
Legionella / immunology*
Legionnaires' Disease / transmission
Maternal-Fetal Exchange*
Pregnancy
Chemical
Reg. No./Substance:
0/Antibodies, Bacterial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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