| Transplacental infection of Coxsackievirus B3 pathological findings in the fetus. | |
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MedLine Citation:
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PMID: 17457913 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Coxsackievirus intrauterine infection has been documented mostly on the basis of indirect evidence of transplacental transmission, with neonatal manifestations ranging from asymptomatic infection to meningoencephalitis, myocarditis, and generalized sepsis. This is the first report of prenatal findings and fetoplacental pathology in a third trimester fetus with coxsackie B3 transplacental infection confirmed by molecular techniques. Prenatal ultrasound detected severe reduction of fetal movements at the 27th week. Late onset fetal akinesia deformation sequence with mild arthrogryposis, necrotic meningoencephalitis with vascular calcifications, interstitial pneumonitis, mild myocardial hypertrophy, and chronic monocytic placental villitis were the cardinal findings at fetal autopsy following interruption of the pregnancy. |
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Authors:
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Anastasia Konstantinidou; Hector Anninos; Nikolaos Spanakis; Xenophon Kotsiakis; Garyfallia Syridou; Athanassios Tsakris; Efstratios Patsouris |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of medical virology Volume: 79 ISSN: 0146-6615 ISO Abbreviation: J. Med. Virol. Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-06-04 Completed Date: 2007-07-30 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7705876 Medline TA: J Med Virol Country: United States |
Other Details:
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Languages: eng Pagination: 754-7 Citation Subset: IM |
Copyright Information:
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(c) 2007 Wiley-Liss, Inc. |
Affiliation:
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Department of Pathology, Medical School, National Kapodistrian University of Athens, Athens, Greece. ankon@med.uoa.gr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Induced Adult Arthrogryposis / pathology Base Sequence Blood Vessels / pathology Calcinosis / pathology Cardiomegaly / pathology Chorionic Villi / pathology Coxsackievirus Infections / pathology*, transmission*, virology Enterovirus B, Human / genetics, isolation & purification* Female Fetal Diseases / pathology* Fetal Movement Fetus / pathology* Histocytochemistry Humans Infectious Disease Transmission, Vertical* Leukoencephalitis, Acute Hemorrhagic / pathology Lung Diseases, Interstitial / pathology Molecular Sequence Data Placenta Diseases / pathology Pregnancy Pregnancy Complications, Infectious Sequence Alignment Ultrasonography, Prenatal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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