| Transplacental Japanese encephalitis virus (JEV) infection in mice during consecutive pregnancies. | |
| | |
MedLine Citation:
|
PMID: 6279773 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Transplacental transmission of Japanese encephalitis virus (JEV) has been demonstrated in consecutive pregnancies of mice. Pregnant mice inoculated intraperitoneally with JEV transmit the virus to the foetus. When such female mice were mated again after 6 months, the virus could be isolated from the foetuses of the ensuing pregnancy. The incidence of abortion was increased significantly though the neonatal deaths were considerably less than during the first pregnancy. Intra-uterine infection occurred in spite of the presence of HAI antibodies against JEV in the preconceptional sera of the mice. The findings of the present study indicate the value of such a system for further investigations of the pathogenesis of JEV infection during pregnancy in humans. |
| | |
Authors:
|
A Mathur; K L Arora; U C Chaturvedi |
Related Documents
:
|
3618673 - Host defense during pregnancy: neutrophil chemotaxis and adherence. 17613713 - Changes in immunoglobulin levels related to herpes simplex virus type 1 brain infection... 10471143 - Reflex sympathetic dystrophy in pregnancy: nine cases and a review of the literature. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Journal of general virology Volume: 59 ISSN: 0022-1317 ISO Abbreviation: J. Gen. Virol. Publication Date: 1982 Mar |
Date Detail:
|
Created Date: 1982-06-14 Completed Date: 1982-06-14 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 0077340 Medline TA: J Gen Virol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 213-7 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abortion, Spontaneous
/
etiology Animals Antibodies, Viral / analysis Encephalitis Virus, Japanese / immunology Encephalitis, Japanese / congenital, transmission* Female Fetal Resorption / etiology Hemagglutination Inhibition Tests Maternal-Fetal Exchange* Mice Pregnancy |
| Chemical | |
Reg. No./Substance:
|
0/Antibodies, Viral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Measurement of surface antigen by specific bacterial adherence and scanning electron microscopy (SAB...
Next Document: Envelope protein of the flavivirus Kunjin is apparently not glycosylated.