Document Detail


Transmyocardial laser revascularization with the CO2 laser: one year results of a randomized, controlled trial.
MedLine Citation:
PMID:  9930706     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Transmyocardial laser revascularization (TMR) was compared to continued medical management in 198 patients with symptomatic end-stage coronary artery disease in a 1:1 randomized prospective study. Angina class, quality of life, and myocardial perfusion significantly improved following TMR over a 12-month period of follow-up. Continued medical management was associated with a higher incidence of unstable anginal episodes, repeat hospitalizations, worsening anginal class and myocardial perfusion. This study demonstrates the superiority of TMR over medical management in the treatment of chronic stable angina. With appropriate patient selection and perioperative management, TMR with the CO2 laser is associated with a very low operative risk.
Authors:
R J March
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial    
Journal Detail:
Title:  Seminars in thoracic and cardiovascular surgery     Volume:  11     ISSN:  1043-0679     ISO Abbreviation:  Semin. Thorac. Cardiovasc. Surg.     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-04-05     Completed Date:  1999-04-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8917640     Medline TA:  Semin Thorac Cardiovasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  12-8     Citation Subset:  IM    
Affiliation:
Rush-Presbyterian-St. Luke's Medical Center, Department of Cardiovascular-Thoracic Surgery, Chicago, IL, USA.
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MeSH Terms
Descriptor/Qualifier:
Coronary Disease / radionuclide imaging,  surgery*,  therapy
Dipyridamole / diagnostic use
Female
Follow-Up Studies
Heart / radionuclide imaging
Humans
Laser Therapy / methods*
Male
Middle Aged
Myocardial Revascularization / methods*
Prospective Studies
Thallium Radioisotopes / diagnostic use
Time Factors
Tomography, Emission-Computed, Single-Photon
Treatment Outcome
Vasodilator Agents / diagnostic use
Chemical
Reg. No./Substance:
0/Thallium Radioisotopes; 0/Vasodilator Agents; 58-32-2/Dipyridamole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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