Document Detail


Transmission of type 1 diabetes by bone marrow transplantation: a case report.
MedLine Citation:
PMID:  18208435     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
T1D after BMT constitutes a human model of autoimmune disease transmission. This case report refers to T1D onset after allogeneic HLA-matched BMT in a six-yr-old recipient affected by aplastic anemia. The donor was his sister who had T1D. The recipient had a complication free course apart from grade 1 acute GVHD, which was resolved spontaneously. With the predictive value and significance of T1D-associated autoantibodies, we tried to consolidate the T1D transfer possibility based on our patient characteristics and a literature review.
Authors:
Fethi Mellouli; Habib Ksouri; Lamia Torjmen; Abderrahman Abdelkefi; Saloua Ladeb; Tarek Ben Othman; Assia Ben Hassen; Mohamed Béjaoui
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-01-16
Journal Detail:
Title:  Pediatric transplantation     Volume:  13     ISSN:  1399-3046     ISO Abbreviation:  Pediatr Transplant     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-01-20     Completed Date:  2009-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9802574     Medline TA:  Pediatr Transplant     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  119-22     Citation Subset:  IM    
Affiliation:
Service d'Immuno-Hématologie pédiatrique, Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia. melloulif@yahoo.fr
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MeSH Terms
Descriptor/Qualifier:
Anemia, Aplastic / surgery
Autoantibodies / analysis
Bone Marrow Transplantation / immunology*
Child
Diabetes Mellitus, Type 1 / immunology*
Graft vs Host Disease / epidemiology
Humans
Male
Tissue Donors
Chemical
Reg. No./Substance:
0/Autoantibodies
Comments/Corrections
Comment In:
Pediatr Transplant. 2009 Feb;13(1):3-6   [PMID:  18785911 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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