Document Detail

Transmission of Hansen's disease and unscreened household contacts.
MedLine Citation:
PMID:  17578265     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Leprosy household contact investigation has been recommended as an epidemiological surveillance strategy for more than 50 years. OBJECTIVE: The purpose of this study was to estimate the yield that could be achieved in case detection if four contacts could be examined for every case found. METHODS: For the estimation of the number of cases not detected (lost) and yield per contact investigation in Mato Grosso, the incidence rates and yield calculations from a cohort study conducted in Rio de Janeiro by Matos et al (1999) were applied to data from the state of Mato Grosso. Also, to identify high-risk groups for leprosy, a cross-sectional study was conducted in which leprosy cases found as a result of a contact investigation were compared with index cases detected by other means. RESULTS: The lost cases among household contacts were at least 4 per every 10 new cases detected. This is the result of insufficient contact investigations--it being 0.8 instead of 4 contact investigations per each case as recommended by the Brazilian Ministry of Health. Up to 60% of the incidence of leprosy could be explained by the high number of lost cases among household contacts not examined. Women and children are more likely to be contacts. CONCLUSION: The lost cases due to insufficient contact investigation represent lost opportunities in early detection and treatment, thus losing the opportunity to reduce leprosy transmission.
E Ignotti; M Bayona; C Alvarez-Garriga; V L G Andrade; J G Valente
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of leprosy     Volume:  79     ISSN:  0254-9395     ISO Abbreviation:  Indian J Lepr     Publication Date:    2007 Jan-Mar
Date Detail:
Created Date:  2007-06-20     Completed Date:  2007-07-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8409173     Medline TA:  Indian J Lepr     Country:  India    
Other Details:
Languages:  eng     Pagination:  11-25     Citation Subset:  IM    
Instituto de Saúde Coletiva (ISC/UFMT), Departmento de Enfermagem (UNEMAT), Universidade Estadual de Mato Grosso, Brazil.
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MeSH Terms
Brazil / epidemiology
Child, Preschool
Contact Tracing*
Family Characteristics*
Leprosy / diagnosis*,  epidemiology,  transmission*
Population Surveillance

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