Document Detail


Transmission of Ebola hemorrhagic fever: a study of risk factors in family members, Kikwit, Democratic Republic of the Congo, 1995. Commission de Lutte contre les Epidémies à Kikwit.
MedLine Citation:
PMID:  9988169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The surviving members of 27 households in which someone had been infected with Ebola virus were interviewed in order to define the modes of transmission of Ebola hemorrhagic fever (EHF). Of 173 household contacts of the primary cases, 28 (16%) developed EHF. All secondary cases had direct physical contact with the ill person (rate ratio [RR], undefined; P < .001), and among those with direct contact, exposure to body fluids conferred additional risk (RR, 3.6; 95% confidence interval [CI], 1.9-6.8). After adjusting for direct contact and exposure to body fluids, adult family members, those who touched the cadaver, and those who were exposed during the late hospital phase were at additional risk. None of the 78 household members who had no physical contact with the case during the clinical illness were infected (upper 95% CI, 4%). EHF is transmitted principally by direct physical contact with an ill person or their body fluids during the later stages of illness.
Authors:
S F Dowell; R Mukunu; T G Ksiazek; A S Khan; P E Rollin; C J Peters
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of infectious diseases     Volume:  179 Suppl 1     ISSN:  0022-1899     ISO Abbreviation:  J. Infect. Dis.     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-02-25     Completed Date:  1999-02-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0413675     Medline TA:  J Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S87-91     Citation Subset:  AIM; IM    
Affiliation:
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. SFD2@cdc.gov
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MeSH Terms
Descriptor/Qualifier:
Adult
Body Fluids / virology
Contact Tracing
Democratic Republic of the Congo / epidemiology
Disease Outbreaks*
Family
Female
Hemorrhagic Fever, Ebola / epidemiology*,  transmission*,  virology
Housing
Humans
Male
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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