Document Detail

Transluminal atherectomy for occlusive peripheral vascular disease.
MedLine Citation:
PMID:  2966573     Owner:  NLM     Status:  MEDLINE    
Sixty-one patients with occlusive peripheral vascular disease were treated with transluminal atherectomy, a catheter-mediated technique for removal of atheroma. The technique was performed using 7Fr, 9Fr or 11Fr atherectomy catheters. Mean percent diameter stenosis was reduced from 71 to 23%, by removal of 831 atheromatous specimens in 949 passes of the cutting element through 136 stenoses in 61 patients. All specimens removed were sent for histopathologic examination to determine the components of the atheroma removed, which differed for specimens removed from original vs restenotic lesions. Percent stenosis was reduced to less than 45% in 118 of 136 stenoses (87%). Complications included 1 thrombus, which resolved after intraarterial infusion of streptokinase and 1 probable distal embolization without sequelae. Three angiographic dissections occurred without impairment of blood flow. There were no instances of acute occlusion, vascular spasm or vessel perforation. Six-month follow-up angiography was performed showing that patients who had a residual stenosis less than 30% after initial atherectomy had a lower restenosis rate (18%) than patients with initial residual stenoses greater than 30% (52%); this result demonstrated the importance of performing more complete atherectomy. Transluminal atherectomy appears to be an effective, predictable and safe method for removing occlusive atheromatous deposits from peripheral arteries.
J B Simpson; M R Selmon; G C Robertson; P R Cipriano; W G Hayden; D E Johnson; T J Fogarty
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  61     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-06-07     Completed Date:  1988-06-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  96G-101G     Citation Subset:  AIM; IM    
Sequoia Hospital, Redwood City, California.
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MeSH Terms
Angioplasty, Balloon / instrumentation,  methods*
Arteriosclerosis / therapy*
Constriction, Pathologic / therapy
Follow-Up Studies
Intermittent Claudication / therapy*
Middle Aged
Time Factors

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