Document Detail


Translocation (6;9;22)(p25;q34;q11.2) identified by FISH in acute leukemia.
MedLine Citation:
PMID:  8956878     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fluorescence in situ hybridization (FISH) study of bone marrow cells from a patient with clinically and immunologically acute leukemia showed that an apparent t(6;22)(p25; q11.2) identified by routine banding techniques concealed a complex t(6;9;22)(p25;q34; q11.2). This observation further supports the importance of FISH in those cases where a chromosome rearrangement could not be reliably detected by conventional cytogenetic study.
Authors:
G J González; M Notohamiprodjo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cancer genetics and cytogenetics     Volume:  92     ISSN:  0165-4608     ISO Abbreviation:  Cancer Genet. Cytogenet.     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1996-12-30     Completed Date:  1996-12-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909240     Medline TA:  Cancer Genet Cytogenet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  82-4     Citation Subset:  IM    
Affiliation:
División de Genética, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Chromosome Banding
Chromosomes, Human, Pair 22*
Chromosomes, Human, Pair 6*
Chromosomes, Human, Pair 9*
Female
Humans
In Situ Hybridization, Fluorescence
Karyotyping
Leukemia / genetics*
Translocation, Genetic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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