Document Detail


Translocation of a discrete piece of deoxyribonucleic acid carrying an amp gene between replicons in Eschericha coli.
MedLine Citation:
PMID:  770415     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A number of well-characterized R plasmids (R1drd 19. K1.R100-1, R46, R55-1, R64-11, R388, and R751) will mobilize an integrated amp gene from the chromosome of Escherichia coli K-12. R391 will not act in this way. The process involves recombination, and in each case the mobilizing plasmid acquires an additional piece of deoxyribonucleic acid of molecular weight 4 X 10(6). Acquisition of this deoxyribonucleic acid may impair the transfer properties of the recombinant plasmid in some cases. The process will occur in a recA background.
Authors:
P M Bennett; M H Richmond
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of bacteriology     Volume:  126     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1976 Apr 
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Ampicillin / pharmacology*
Carbenicillin / pharmacology
Chromosome Aberrations*
DNA, Bacterial* / analysis
DNA, Circular / analysis
Escherichia coli / analysis,  drug effects*
Genes*
Molecular Weight
Mutation
Penicillin Resistance*
R Factors*
Recombination, Genetic
Translocation, Genetic*
Trimethoprim / pharmacology
Chemical
Reg. No./Substance:
0/DNA, Bacterial; 0/DNA, Circular; 4697-36-3/Carbenicillin; 69-53-4/Ampicillin; 738-70-5/Trimethoprim
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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