| Translation deregulation in B-cell lymphomas. | |
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MedLine Citation:
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PMID: 21118132 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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B-cell lymphomas are a heterogeneous group of diseases that can arise at different stages of B-cell development, often as a result of errors in the cells' unique ontogeny. Common oncogenic features are often observed, including chromosomal rearrangements, somatic mutations and transcriptional change. Disruption of translation regulation is also frequently implicated in both B-cell lymphoma development and progression. Deregulation of translation in lymphomagenesis can arise through changes to the proteins constituting the translational machinery or to their regulators, and to changes in miRNA (microRNA) expression. |
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Authors:
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Emilie Horvilleur; Lindsay A Wilson; Anne E Willis |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biochemical Society transactions Volume: 38 ISSN: 1470-8752 ISO Abbreviation: Biochem. Soc. Trans. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7506897 Medline TA: Biochem Soc Trans Country: England |
Other Details:
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Languages: eng Pagination: 1593-7 Citation Subset: IM |
Affiliation:
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MRC Toxicology Unit, Hodgkin Building, P.O. Box 138, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK. eh118@le.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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//Biotechnology and Biological Sciences Research Council; //Cancer Research UK |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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