Document Detail

Transjugular intrahepatic portosystemic shunts (TIPS): a decade later.
MedLine Citation:
PMID:  10636206     Owner:  NLM     Status:  MEDLINE    
Since the introduction of transjugular intrahepatic portosystemic shunt (TIPS) 10 years ago, it has been used increasingly in the management of portal hypertension and its complications. TIPS is now considered the procedure of choice for management of refractory variceal bleeding. Its role in the management of refractory ascites, hepatic hydrothorax, hepatorenal syndrome, and hepatopulmonary syndrome still awaits further prospective studies. The two main complications of TIPS are hepatic encephalopathy and shunt malfunction. Generally, TIPS stenosis or occlusion is a major drawback requiring routine surveillance of TIPS with doppler ultrasound. Venography with balloon dilation of the stent or placement of serial or parallel stents may be required in some cases. Promising modalities of preventing TIPS malfunction (e.g., brachy-therapy, covered stents, or anti-platelet derived growth factor) are currently being investigated.
J P Ong; M Sands; Z M Younossi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of clinical gastroenterology     Volume:  30     ISSN:  0192-0790     ISO Abbreviation:  J. Clin. Gastroenterol.     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-02-02     Completed Date:  2000-02-02     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7910017     Medline TA:  J Clin Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  14-28     Citation Subset:  IM    
Department of Gastroenterology, Cleveland Clinic Foundation, Ohio 44195, USA.
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MeSH Terms
Acute Disease
Ascites / therapy
Budd-Chiari Syndrome / therapy
Hemorrhage / therapy
Hypertension, Portal / complications,  therapy*
Portasystemic Shunt, Transjugular Intrahepatic* / adverse effects,  contraindications,  methods

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