| Transjugular intrahepatic portosystemic shunt versus endoscopic sclerotherapy in the elective treatment of recurrent variceal bleeding. | |
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MedLine Citation:
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PMID: 20819451 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study was designed to compare elective transjugular intrahepatic portosystemic shunts (TIPS) and endoscopic sclerotherapy (EST) in terms of their efficacy in preventing recurrent bleeding from gastro-oesophageal varices in patients with advanced liver cirrhosis and portal hypertension. Of 96 patients with at least three gastro-oesophageal variceal rebleeds, 50 were treated with elective TIPS and 46 with EST. Recurrent variceal bleeding was significantly more frequent in patients receiving EST treatment compared with those receiving TIPS (45.7% versus 6.3%, respectively). Cumulative 1- and 4-year survival in the TIPS group was 83.0% and 73.5%, respectively, compared with 69.8% and 39.8% in the EST group, respectively. The rate of portosystemic encephalopathy was 33.3% in the TIPS group and 37.0% in the EST group. Elective TIPS was more effective than EST in the prevention of gastro-oesophageal variceal rebleeding in cirrhotic patients, it improved survival and it was associated with a similar rate of portosystemic encephalopathy. |
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Authors:
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P Popovic; B Stabuc; P Skok; M Surlan |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Journal of international medical research Volume: 38 ISSN: 0300-0605 ISO Abbreviation: J. Int. Med. Res. Publication Date: 2010 May-Jun |
Date Detail:
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Created Date: 2010-09-07 Completed Date: 2010-09-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0346411 Medline TA: J Int Med Res Country: England |
Other Details:
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Languages: eng Pagination: 1121-33 Citation Subset: IM |
Affiliation:
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Clinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia. peter.popovic@kclj.si |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Equipment Failure Esophageal and Gastric Varices / etiology, mortality, surgery* Esophagoscopy Female Humans Hypertension, Portal / complications, mortality, surgery Liver Cirrhosis / complications, mortality, surgery Male Middle Aged Portasystemic Shunt, Transjugular Intrahepatic* Retrospective Studies Sclerotherapy* Slovenia / epidemiology Stents Survival Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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