Document Detail

Transjugular intrahepatic portosystemic shunt versus endoscopic sclerotherapy in the elective treatment of recurrent variceal bleeding.
MedLine Citation:
PMID:  20819451     Owner:  NLM     Status:  MEDLINE    
The present study was designed to compare elective transjugular intrahepatic portosystemic shunts (TIPS) and endoscopic sclerotherapy (EST) in terms of their efficacy in preventing recurrent bleeding from gastro-oesophageal varices in patients with advanced liver cirrhosis and portal hypertension. Of 96 patients with at least three gastro-oesophageal variceal rebleeds, 50 were treated with elective TIPS and 46 with EST. Recurrent variceal bleeding was significantly more frequent in patients receiving EST treatment compared with those receiving TIPS (45.7% versus 6.3%, respectively). Cumulative 1- and 4-year survival in the TIPS group was 83.0% and 73.5%, respectively, compared with 69.8% and 39.8% in the EST group, respectively. The rate of portosystemic encephalopathy was 33.3% in the TIPS group and 37.0% in the EST group. Elective TIPS was more effective than EST in the prevention of gastro-oesophageal variceal rebleeding in cirrhotic patients, it improved survival and it was associated with a similar rate of portosystemic encephalopathy.
P Popovic; B Stabuc; P Skok; M Surlan
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of international medical research     Volume:  38     ISSN:  0300-0605     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-09-07     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1121-33     Citation Subset:  IM    
Clinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
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MeSH Terms
Equipment Failure
Esophageal and Gastric Varices / etiology,  mortality,  surgery*
Hypertension, Portal / complications,  mortality,  surgery
Liver Cirrhosis / complications,  mortality,  surgery
Middle Aged
Portasystemic Shunt, Transjugular Intrahepatic*
Retrospective Studies
Slovenia / epidemiology
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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