| Transition from donor candidates to live kidney donors: the impact of race and undiagnosed medical disease states. | |
| | |
MedLine Citation:
|
PMID: 20047616 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Norman SP, Song PXK, Hu Y, Ojo AO. Transition from donor candidates to live kidney donors: the impact of race and undiagnosed medical disease states. Clin Transplant 2011: 25: 136-145. © 2009 John Wiley & Sons A/S. Abstract: Background: Living kidney donors (LKD) allow for increased access to lifesaving organs for transplantation. There is a relative paucity of African American (AA) live kidney donors. The prevalence of medical disease in LKD candidates has not been well studied. We examined the medical limitations to living kidney donation in a large Midwestern transplant center. Methods: A total of 2519 adults (age ≥ 18 ) evaluated as potential LKD (PD) between January 1, 1996 and June 30, 2006 were prospectively followed until evaluation outcome (completed live donation, medical exclusion from live donation, non-medical exclusion from live donation). Logistic regression was used to examine the effect of age on donor exclusion, and chi-square tests were used to compare the likelihood of donor exclusions between racial and gender groups. Results: Sixty percent of PD were female (n = 1300), and 86% were Caucasian (CA) (n = 1862). Overall, 48.7% of PD who underwent evaluation became LKD. The odds of donation were 52% lower in AA compared to CA (OR 0.48 p < 0.001). Among PD excluded from donation, the most common medical diagnoses were hypertension (HTN) (24.7%), inadequate creatinine clearance (10.6%) and a positive final crossmatch (10.5%). The rate of PD exclusion for obesity was twofold higher in AA compared to CA (12.8% vs. 5.8%, p < 0.001). Conclusions: Hypertension in PD is equally significant barrier to living kidney donation in AA and CA whereas obesity is a greater barrier in AA. |
| | |
Authors:
|
Silas P Norman; Peter X K Song; Youna Hu; Akinlolu O Ojo |
Related Documents
:
|
2531906 - Evaluation of the efficacy of chlortetracycline for the control of chronic respiratory ... 735986 - Evaluation of suicide risk. 10485106 - Timing in relay running. 20707636 - Quantitative evaluation of the effects of subthalamic stimulation on gait in parkinson'... 21889706 - Ethics of re-hearsing procedures on a corpse. 9793106 - Addiction to benzodiazepines. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical transplantation Volume: 25 ISSN: 1399-0012 ISO Abbreviation: Clin Transplant Publication Date: 2011 Jan |
Date Detail:
|
Created Date: 2011-02-08 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8710240 Medline TA: Clin Transplant Country: Denmark |
Other Details:
|
Languages: eng Pagination: 136-45 Citation Subset: IM |
Copyright Information:
|
© 2009 John Wiley & Sons A/S. |
Affiliation:
|
Department of Internal Medicine School of Public Health, University of Michigan, Ann Arbor, Michigan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparison of biliary complications in adult living-donor liver transplants performed at two busy tr...
Next Document: The association between eNOS intron 4 VNTR polymorphism and delayed graft function of kidney allogra...