Document Detail

Transition dynamics in experimental gingivitis in humans.
MedLine Citation:
PMID:  2528625     Owner:  NLM     Status:  MEDLINE    
This study was conducted in order to investigate the dynamics of the gingival inflammatory status during periods of plaque accumulation and thorough oral hygiene. After a period of prophylaxis, 42 volunteers were asked to abstain from all oral hygiene measures for 2 weeks, whereafter oral hygiene was reinstituted. In the absence of oral hygiene, plaque was found at virtually all sites after 7 days and the number of sites with gingivitis increased simultaneously. A reduction in gingival inflammation occurred subsequent to plaque removal. During phases of both plaque accumulation and thorough oral hygiene, sites were found to convert from non-inflamed to inflamed status concurrently, as in the reverse direction. No association between plaque and gingivitis was revealed. The gingival status of a single site was a poor predictor of its status on the subsequent occasion. The proportion of inflamed sites converting to non-inflamed status was greater than the proportion of non-inflamed sites converting to inflamed status at any time. The estimated incidence rate remained fairly constant during both the plaque accumulation phase and the oral hygiene phase, whereas the estimated recovery rate was considerable lower during the plaque accumulation phase compared to oral hygiene phase. The clinical appearance is the outcome of the dynamics between these rates. The steady-state prevalences derived from the estimated "incidence" and "recovery" rates were quite similar to the actual findings after 14 d of plaque accumulation and the subsequent 10 d of thorough oral hygiene.
B Danielsen; F Manji; N Nagelkerke; O Fejerskov; V Baelum
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of periodontal research     Volume:  24     ISSN:  0022-3484     ISO Abbreviation:  J. Periodont. Res.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-10-26     Completed Date:  1989-10-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0055107     Medline TA:  J Periodontal Res     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  254-60     Citation Subset:  D; IM    
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MeSH Terms
Dental Plaque / physiopathology*,  prevention & control
Dental Plaque Index
Dental Prophylaxis
Gingiva / physiology
Gingivitis / physiopathology*,  prevention & control
Oral Hygiene
Periodontal Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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