Document Detail

Transition-Metal-free Hydroamination Reaction of N-Substituted-2-Alkynamides with Hydrazides via Sequential Ugi/Nucleophilic Addition Reaction.
MedLine Citation:
PMID:  23734677     Owner:  NLM     Status:  Publisher    
Five-component sequential Ugi/nucleophilic addition reaction of aromatic aldehydes, primary amines, propiolic acid, isocyanides and hydrazides has been developed in order to access polyfunctional pseudopeptides. The reaction may proceed through formation of N-substituted-2-alkynamides as intermediates. This process is found to be mild and operationally simple with broad substrate scope.
Shokoofeh Maghari; Sorour Ramezanpour; Saeed Balalaie; Fatemeh Darvish; Frank Rominger; Hamid Reza Bijanzadeh
Related Documents :
23620437 - Enantioselective construction of highly substituted vinylidenecylopentanes by palladium...
23852827 - Cu-catalyzed formal methylative and hydrogenative carboxylation of alkynes with carbon ...
23738857 - Synthesis of cis-c-iodo-n-tosyl-aziridines using diiodomethyllithium. reaction optimiza...
23034237 - High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer.
2844307 - Ligninase-mediated phenoxy radical formation and polymerization unaffected by cellobios...
21916477 - Regioselective synthesis of 1,3,5-substituted benzenes via the incl3/2-iodophenol-catal...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-6-5
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  -     ISSN:  1520-6904     ISO Abbreviation:  J. Org. Chem.     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-6-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Simple and Sustainable Iron-Catalyzed Aerobic C-H Functionalization of N,N Dialkylanilines.
Next Document:  De novo inference of stratification and local admixture in sequencing studies.