Document Detail

Transient symptomatic zinc deficiency in a breast-fed preterm infant.
MedLine Citation:
PMID:  17958805     Owner:  NLM     Status:  MEDLINE    
Transient, symptomatic zinc deficiency in breast-fed, low-birthweight infants is a rare, but probably underrecognized disorder hallmarked by periorificial and acral dermatitis. Unlike in acrodermatitis enteropathica, symptoms disappear when nursing ends. We report a breast-fed, preterm infant with demarcated, erythematous, and exudative patches with overlying crusts on the perioral, perianal, and acral areas. Laboratory investigations revealed lowered zinc levels in the infant's serum, but normal levels in his mother's milk. Oral zinc supplementation resulted in total clearing of skin lesions within 4 weeks. Our patient's presentation illustrates the importance of zinc in rapidly growing preterm infants and aims to stimulate awareness for this disorder. Symptomatic zinc deficiency can be easily diagnosed by careful examination and effectively treated with oral zinc substitution.
Ursula Kiechl-Kohlendorfer; Franz-Martin Fink; Elisabeth Steichen-Gersdorf
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric dermatology     Volume:  24     ISSN:  1525-1470     ISO Abbreviation:  Pediatr Dermatol     Publication Date:    2007 Sep-Oct
Date Detail:
Created Date:  2007-10-25     Completed Date:  2007-12-06     Revised Date:  2009-03-03    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  536-40     Citation Subset:  IM    
Department of Pediatrics, Division of Neonatology, Neuropediatrics and Metabolic Diseases, Innsbruck Medical University, Innsbruck, Austria.
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MeSH Terms
Breast Feeding*
Gluconates / administration & dosage*
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature*
Skin Diseases / diet therapy*,  etiology*,  metabolism
Zinc / blood,  deficiency*
Reg. No./Substance:
0/Gluconates; 526-95-4/gluconic acid; 7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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