| Transient suppression of seizures by repetitive transcranial magnetic stimulation in a case of Rasmussen's encephalitis. | |
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MedLine Citation:
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PMID: 18304879 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Repetitive transcranial magnetic stimulation (rTMS) has been applied with variable success to terminate the seizures of epilepsia partialis continua. The rationale for using this technique to suppress ongoing seizures is the capacity of rTMS to interrupt ongoing neuronal activity, and to produce a lasting decrease in cortical excitability with low-frequency (1 Hz) stimulation. We report a case of epilepsia partialis continua in a child with Rasmussen's encephalitis, in whom seizures were transiently suppressed by 1-Hz rTMS delivered in nine daily 30-minute sessions. In this case, total ictal time was significantly reduced during stimulation, but the daily baseline seizure rate remained unchanged. Notably, the detection and quantification of this short-lived improvement were enabled by recording EEG continuously during the rTMS session. Thus, we present this case to illustrate a potential utility of combined continuous EEG recording and rTMS in seizure treatment. |
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Authors:
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Alexander Rotenberg; Dewi Depositario-Cabacar; Erica Hyunji Bae; Chellamani Harini; Alvaro Pascual-Leone; Masanori Takeoka |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2008-03-04 |
Journal Detail:
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Title: Epilepsy & behavior : E&B Volume: 13 ISSN: 1525-5069 ISO Abbreviation: Epilepsy Behav Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-06-16 Completed Date: 2008-09-04 Revised Date: 2013-03-21 |
Medline Journal Info:
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Nlm Unique ID: 100892858 Medline TA: Epilepsy Behav Country: United States |
Other Details:
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Languages: eng Pagination: 260-2 Citation Subset: IM |
Affiliation:
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Division of Epilepsy and Clinical Neurophysiology, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. alexander.rotenberg@childrens.harvard.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Electric Stimulation / methods Electroencephalography Encephalitis / complications Epilepsia Partialis Continua / etiology, therapy* Evoked Potentials, Motor Humans Male Transcranial Magnetic Stimulation / methods* |
| Grant Support | |
ID/Acronym/Agency:
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K24 RR018875/RR/NCRR NIH HHS; K24 RR018875/RR/NCRR NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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