Document Detail

Transient short free running circadian rhythm in a case of aneurysm near the suprachiasmatic nuclei.
MedLine Citation:
PMID:  16024905     Owner:  NLM     Status:  MEDLINE    
A free running circadian rest-activity cycle is rare in sighted individuals living in a normal environment. Even more rare is a periodicity shorter than 24 hours, as observed in actigraphic recordings in a female patient during convalescence after a whiplash injury in a car accident. The documented free running period was 22.5 hours for 19 days. During the subsequent weeks re-entrainment occurred following re-establishment by a social zeitgeber, with a slightly early circadian phase of nocturnal melatonin onset relative to a late sleep period. Magnetic resonance imaging and cerebral angiography showed an aneurysm at the bifurcation of the right internal carotid artery, close to the circadian pacemaker structure (the suprachiasmatic nuclei), which was later occluded.
K E Bloch; T Brack; A Wirz-Justice
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  76     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-07-18     Completed Date:  2005-09-06     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  1178-80     Citation Subset:  IM    
Sleep Disorders Centre, Pulmonary Division, University Hospital of Zürich, Rämistrasse 100, CH-8091 Zürich, Switzerland.
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MeSH Terms
Chronobiology Disorders / diagnosis,  etiology*
Disorders of Excessive Somnolence / diagnosis,  etiology
Intracranial Aneurysm / complications,  pathology*
Magnetic Resonance Imaging
Suprachiasmatic Nucleus / blood supply*,  pathology*
Time Factors
Whiplash Injuries / complications
Comment In:
J Neurol Neurosurg Psychiatry. 2005 Aug;76(8):1044   [PMID:  16024875 ]

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