Document Detail

Transient severe brain stem depression during intraarterial papaverine infusion for cerebral vasospasm.
MedLine Citation:
PMID:  8010275     Owner:  NLM     Status:  MEDLINE    
A 63-year-old woman had severe, symptomatic cerebral vasospasm secondary to subarachnoid hemorrhage. We initiated simultaneous infusions of papaverine into her left vertebral and left internal carotid arteries. Twenty-five minutes after the infusions had begun, the patient had a transient reaction of respiratory arrest followed by rapid, progressive loss of brain stem function.
J D Barr; J M Mathis; J A Horton
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  15     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  1994 Apr 
Date Detail:
Created Date:  1994-07-21     Completed Date:  1994-07-21     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  719-23     Citation Subset:  IM    
Department of Radiology, University of Pittsburgh, PA.
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MeSH Terms
Apnea / chemically induced*
Basilar Artery / drug effects
Brain Stem / drug effects*
Infusions, Intra-Arterial
Intracranial Aneurysm / complications
Ischemic Attack, Transient / drug therapy*,  etiology
Middle Aged
Papaverine / administration & dosage,  adverse effects*
Subarachnoid Hemorrhage / complications
Vasoconstriction / drug effects
Vertebral Artery / drug effects
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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