Document Detail

Transient otoacoustic emissions in the detection of olivocochlear bundle maturation.
MedLine Citation:
PMID:  16198429     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The medial olivocochlear bundle, forms a neural pathway connecting the superior olivary complex to the outer hair cells of mainly the contralateral cochlea. Although the biological significance of the bundle remains ambiguous, it is clear that activation of medial olivocochlear fibers alters cochlear output and this can be experimentally evident through a series of changes on otoacoustic emissions, called otoacoustic emission suppression. The aim of this study is to observe the maturation of the medial olivocochlear bundle by measuring the suppression effects on transient otoacoustic emissions. METHODS: The study population consisted of 27 premature babies (53 ears) from the P&A Kyriakou Neonatal Intensive Care Unit (conceptional age: 31-36 weeks) and 43 fullterm babies (61 ears) (conceptional age: 37-42 weeks) from the same unit. The ILO-92 system is used to deliver both the linear clicks to the ear examined (producing the emissions) and the white noise to the contralateral ear. The mode used is based on the alternating on and off presence of the white noise in the contralateral ear. RESULTS: 12/53 (22%) ears of preterm babies presented suppression > or =1 dB. 32/61 (52.4%) ears of fullterm babies presented suppression > or =1 dB. The mean suppression for the ears of premature infants was 0.52 dB, (+/-0.1 S.E.M.). The mean suppression for the ears of fullterm infants was 0.90 dB, (+/-0.09 S.E.M.). At the second half of the time window, suppression of fullterms rises above 1 dB (a pattern similar to that of adults), whereas it remains below 1 dB for preterms. CONCLUSIONS: Suppression of otoacoustic emissions helps us to study the function of the medial olivocochlear bundle in different populations. It appears in premature babies but becomes stronger as the postconceptional age advances.
Eleni Gkoritsa; Michael Tsakanikos; Stavros Korres; Heracles Dellagrammaticas; N Apostolopoulos; Eleftherios Ferekidis
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Publication Detail:
Type:  Journal Article     Date:  2005-09-29
Journal Detail:
Title:  International journal of pediatric otorhinolaryngology     Volume:  70     ISSN:  0165-5876     ISO Abbreviation:  Int. J. Pediatr. Otorhinolaryngol.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-02-28     Completed Date:  2006-09-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8003603     Medline TA:  Int J Pediatr Otorhinolaryngol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  671-6     Citation Subset:  IM    
ENT Department of Athens National University, Hippokration Hospital, 114 Vas. Sofias Av., GR-11528 Athens, Greece.
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MeSH Terms
Acoustic Stimulation / methods
Age Factors
Aging / physiology*
Auditory Pathways / physiology
Child Development
Cluster Analysis
Cochlea / growth & development,  physiology*
Gestational Age
Hair Cells, Auditory, Outer / physiology
Infant, Newborn
Infant, Premature / physiology*
Olivary Nucleus / physiology*
Otoacoustic Emissions, Spontaneous / physiology*

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