Document Detail

Transient neonatal hypocalcemia, hypomagnesemia, and high serum parathyroid hormone with maternal hyperparathyroidism.
MedLine Citation:
PMID:  1169899     Owner:  NLM     Status:  MEDLINE    
Findings in a case of neonatal tetany in a child whose mother had elevated blood parathyroid hormone levels because of a parathyroid adenoma are given. The child was found to have hypocalcemia, hypomagnesemia, and hyperphosphatemia. Parathyroid hormone in the infant was found to be elevated. It has been postulated that the pathophysiologic mechanism of the hypocalcemia in this syndrome is transient hypoparathyroidism. The present case suggests a different mechanism: hypomagnesemia and end-organ refractoriness to parathyroid hormone, a state analogous to pseudohypoparathyroidism.
J A Monteleone; J B Lee; A H Tashjian; H E Cantor
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Annals of internal medicine     Volume:  82     ISSN:  0003-4819     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  1975 May 
Date Detail:
Created Date:  1975-08-22     Completed Date:  1975-08-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  670-2     Citation Subset:  AIM; IM    
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MeSH Terms
Adenoma / complications
Hyperparathyroidism / complications*
Hypocalcemia / etiology*
Hypoparathyroidism / physiopathology
Infant, Newborn
Infant, Newborn, Diseases / etiology*
Magnesium / blood*
Maternal-Fetal Exchange*
Parathyroid Hormone / blood*
Parathyroid Neoplasms / complications
Pregnancy Complications*
Tetany / etiology
Time Factors
Reg. No./Substance:
0/Parathyroid Hormone; 7439-95-4/Magnesium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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