| Transient hypoxia: ventilatory response after vagotomy and during artificial phasic inflation. | |
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MedLine Citation:
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PMID: 34825 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The early ventilatory response to transient hypoxia was examined in the anaesthetized rabbit. In intact spontaneously breathing animals, an increase in tidal volume (VT) with an accompanying slight increase in inspiratory duration (TI) and a decrease in the expiratory duration (TE) was observed. After vagotomy, the ventilatory response was distinguished by a greater increase in VT and a significant decrease in TI and TE. In another group of artificially ventilated rabbits, an increase in inspiratory volume with a simultaneous decrease in breathing frequency was found to involve a smaller reflex increase in phrenic inspiratory discharge after onset of transient hypoxia. These observations suggest that afferents from pulmonary vagal stretch receptors inhibit those from arterial chemoreceptors. |
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Authors:
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S Delpierre; C Guillot; M Fornaris; Y Jammes; C Grimaud |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pflügers Archiv : European journal of physiology Volume: 379 ISSN: 0031-6768 ISO Abbreviation: Pflugers Arch. Publication Date: 1979 Feb |
Date Detail:
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Created Date: 1979-06-26 Completed Date: 1979-06-26 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0154720 Medline TA: Pflugers Arch Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 53-7 Citation Subset: IM; S |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anoxia / blood, physiopathology* Carbon Dioxide / blood Chemoreceptor Cells / physiology Hydrogen-Ion Concentration Lung / innervation* Mechanoreceptors / physiology Oxygen / blood Phrenic Nerve / physiology Rabbits Respiration* Vagotomy Vagus Nerve / physiology* |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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