Document Detail

Transient hyperthyroidism following L-asparaginase therapy for acute lymphoblastic leukemia.
MedLine Citation:
PMID:  11221167     Owner:  NLM     Status:  MEDLINE    
The effect of L-asparaginase on the thyroid gland has not been well documented. We report the first two cases of hyperthyroidism associated with thyroid nodule following L-asparaginase therapy for acute lymphoblastic leukemia (ALL). The thyroid function abnormalities were not severe, short-lived and did not require specific therapy.
S A Fadilah; I Faridah; S K Cheong
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Medical journal of Malaysia     Volume:  55     ISSN:  0300-5283     ISO Abbreviation:  Med. J. Malaysia     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-02-26     Completed Date:  2001-03-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0361547     Medline TA:  Med J Malaysia     Country:  Malaysia    
Other Details:
Languages:  eng     Pagination:  513-5     Citation Subset:  IM    
Department of Haematology and Transplantation, MAKNA-HUKM Cancer Institute, Hospital Universiti Kebangsaan Malaysia, Jalan Tenteram, Cheras, 56000 Kuala Lumpur.
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MeSH Terms
Antineoplastic Agents / adverse effects*,  therapeutic use
Asparaginase / adverse effects*,  therapeutic use
Hyperthyroidism / chemically induced*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
Time Factors
Reg. No./Substance:
0/Antineoplastic Agents; EC

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