Document Detail


Transient hyperammonemia associated with postictal state in generalized convulsion.
MedLine Citation:
PMID:  21943818     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Previous studies revealed that transient hyperammonemia was noted after generalized convulsion. This study was undertaken to analyze the association between postictal state and serum ammonia levels. Adult patients presenting to the emergency department with seizures were included. Serum ammonia and other blood tests were compared between patients with full recovery of consciousness after generalized convulsion and those who had not completely regained consciousness. Patients who had not completely regained consciousness (7 of 7, 100%) had higher rate (p=0.035) of hyperammonemia compared with patients who had fully regained consciousness (4 of 10, 40%) and higher level of serum ammonia (246±96μg/dL vs. 102±99μg/dL, p=0.006). All patients who showed postictal consciousness level impairment on arrival at the emergency department had elevated serum ammonia at that time. Transient hyperammonemia is associated with postictal confusion.
Authors:
Kuan-Ting Liu; Shih-Chia Yang; I-Jeng Yeh; Tzeng-Jih Lin; Chi-Wei Lee
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Publication Detail:
Type:  -     Date:  2011-7-23
Journal Detail:
Title:  The Kaohsiung journal of medical sciences     Volume:  27     ISSN:  1607-551X     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-9-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100960562     Medline TA:  Kaohsiung J Med Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  453-456     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier B.V.
Affiliation:
Department of Emergency Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
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