| Transient hepatic echogenicity difference on contrast-enhanced ultrasonography: sonographic sign and pitfall. | |
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MedLine Citation:
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PMID: 17324983 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to report and analyze a new contrast-enhanced ultrasonographic (CEUS) imaging finding, the transient hepatic echogenicity difference due to perfusion changes, using computed tomography (CT) as a reference standard. METHODS: We retrospectively investigated the records of patients evaluated in a 2-year period, selecting those who had undergone both CT and CEUS within 15 days, who had CT evidence of a perfusion abnormality, and who had had a CEUS study that included the malperfused parenchymal area. RESULTS: There were 30 patients with 44 hepatic perfusion changes on CT scans (28 around liver focal lesions and 16 unrelated to focal lesions). Retrospectively, CEUS allowed recognition of 21 of 28 perifocal transient hepatic attenuation differences (THADs), 6 of 10 subsegmental THADs, 2 of 3 segmental THADs, and 1 of 3 lobar THADs. Only some of these abnormalities had been identified at the original CEUS examinations: 0 of 3 lobar THADs, 1 of 3 segmental THADs, 2 of 10 subsegmental THADs, and 16 of 28 perifocal THADs. CONCLUSIONS: Contrast-enhanced ultrasonography can show hepatic perfusion abnormalities similar to those well known from CT literature, although with a lower sensitivity. Knowledge of this transient hepatic echogenicity difference phenomenon may be relevant for avoiding incorrect image interpretation or incorrect tumor size measurement and for eventually identifying occult vascular disorders such as venous thrombosis or fistulas. |
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Authors:
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Orlando Catalano; Fabio Sandomenico; Antonio Nunziata; Mauro Mattace Raso; Paolo Vallone; Alfredo Siani |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine Volume: 26 ISSN: 0278-4297 ISO Abbreviation: J Ultrasound Med Publication Date: 2007 Mar |
Date Detail:
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Created Date: 2007-02-27 Completed Date: 2007-04-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211547 Medline TA: J Ultrasound Med Country: United States |
Other Details:
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Languages: eng Pagination: 337-45 Citation Subset: IM |
Affiliation:
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Department of radiology, National Cancer Institute Fondazione G. Pascale, Naples, Italy. orlandcat@tin.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Carcinoma, Hepatocellular / secondary, ultrasonography* Contrast Media Female Humans Image Processing, Computer-Assisted Liver / blood supply, ultrasonography* Liver Circulation / physiology* Liver Neoplasms / ultrasonography* Male Middle Aged Phospholipids Retrospective Studies Sensitivity and Specificity Sulfur Hexafluoride Tomography, X-Ray Computed Ultrasonography / methods |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Phospholipids; 0/contrast agent BR1; 2551-62-4/Sulfur Hexafluoride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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