Document Detail

Transient global amnesia and functional retrograde amnesia: contrasting examples of episodic memory loss.
MedLine Citation:
PMID:  9415927     Owner:  NLM     Status:  MEDLINE    
We studied 11 patients with transient global amnesia (TGA) and ten patients with functional retrograde amnesia (FRA). Patients with TGA had a uniform clinical picture: a severe, relatively isolated amnesic syndrome that started suddenly, persisted for 4-12 h, and then gradually improved to essentially normal over the next 12-24 h. During the episode, the patients had severe anterograde amnesia for verbal and non-verbal material and retrograde amnesia that typically covered at least two decades. Thirty hours to 42 days after the episode, the patients had recovered completely and performed normally on tests of anterograde and retrograde amnesia. By contrast, patients with FRA had a sudden onset of memory problems that were characterized by severe retrograde amnesia without associated anterograde amnesia and with a clinical presentation that otherwise varied considerably. The episodes persisted from several weeks to more than two years, and some of the patients had not recovered at the time of our last contact with them. The uniform clinical picture of TGA and the variable clinical picture of FRA presumably reflect their respective neurologic ('organic') and psychogenic ('non-organic') aetiologies.
M Kritchevsky; J Zouzounis; L R Squire
Related Documents :
1666127 - Sinus histiocytosis with massive lymphadenopathy (rosai-dorfman disease) in a patient w...
22714607 - Conservatively treated perforation of the neovagina in a male to female transsexual pat...
1267987 - Spontaneous variations in atrioventricular conduction in pre-excitation.
23079047 - Iron deposition in the precentral grey matter in patients with multiple sclerosis: a qu...
22130047 - Vagus nerve stimulation has a positive effect on mood in patients with refractory epile...
20659127 - Toll-like receptor (tlr)-9 genetics and function in sarcoidosis.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Philosophical transactions of the Royal Society of London. Series B, Biological sciences     Volume:  352     ISSN:  0962-8436     ISO Abbreviation:  Philos. Trans. R. Soc. Lond., B, Biol. Sci.     Publication Date:  1997 Nov 
Date Detail:
Created Date:  1998-01-28     Completed Date:  1998-01-28     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7503623     Medline TA:  Philos Trans R Soc Lond B Biol Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1747-54     Citation Subset:  IM    
Department of Neurosciences, University of California, San Diego 92093, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amnesia, Retrograde*
Memory Disorders*
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Source monitoring and memory distortion.
Next Document:  Memory and anxiety disorders.