| Transient eruptive seborrheic keratoses associated with erythrodermic psoriasis and erythrodermic drug eruption: report of two cases. | |
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MedLine Citation:
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PMID: 11712062 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The appearance of multiple seborrheic keratoses in association with underlying internal malignancy (known as the sign of Leser-Trelat) has generated much discussion and debate in the literature. However, comparatively few case reports exist that examine the appearance of multiple seborrheic keratoses associated with exfoliative erythroderma without underlying malignancy. We report 2 cases in which multiple, biopsy-proven seborrheic keratoses appeared in conjunction with erythrodermic skin eruptions. The underlying diseases in these 2 patients included psoriasis and an eczematous drug eruption; in both cases the erythroderma resolved with appropriate treatment. After resolution of the erythroderma, the newly developed seborrheic keratoses proceeded to involute and gradually fall off. Neither of the patients exhibited any evidence of internal malignancy. These cases represent the first reports of psoriasis and drug eruption as causes of erythroderma-induced transient eruptive seborrheic keratoses. Clinical and pathologic findings are consistent with previous descriptions of this entity. |
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Authors:
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S L Flugman; S A McClain; R A Clark |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of the American Academy of Dermatology Volume: 45 ISSN: 0190-9622 ISO Abbreviation: J. Am. Acad. Dermatol. Publication Date: 2001 Dec |
Date Detail:
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Created Date: 2001-11-16 Completed Date: 2001-12-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7907132 Medline TA: J Am Acad Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: S212-4 Citation Subset: IM |
Affiliation:
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Department of Dermatology, State University of New York at Stony Brook, USA. ScottFMD@aol.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Diagnosis, Differential Drug Eruptions / diagnosis*, etiology, pathology Female Humans Keratolytic Agents / adverse effects* Keratosis, Seborrheic / chemically induced, diagnosis*, pathology Male Psoriasis / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Keratolytic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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