Document Detail

Transient and distortion product evoked oto-acoustic emissions in normal hearing patients with and without tinnitus.
MedLine Citation:
PMID:  18359362     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To test the hypothesis that tinnitus begins with outer hair cell dysfunction by recording transient (TEOAE) and distortion product evoked (DPOAE) oto-acoustic emissions in patients with normal hearing with (study group, SG) and without tinnitus (control group, CG). STUDY DESIGN: Case control study. SUBJECTS AND METHODS: SG had 32 patients with pure tone thresholds below 25 dB in the 500 to 8000 Hz interval. CG had 37 age- and gender-matched patients with similar thresholds. All patients had normal tympanograms and stapedial reflexes. TEOAE were recorded with wide band click in continuous mode at 80-dB peak SPL. DPOAE were recorded with f1/f2 = 1.22 and intensities of 65 dB (f1) and 55 dB (f2) SPL. RESULTS: DPOAE were abnormal in 68.4% of SG and in 50% of CG (P = 0.036). TEOAE were abnormal in 70.2% of SG and in 16.10% of CG (P = 0.0001). CONCLUSION: SG had significantly higher prevalence of abnormal TEOAE and DPOAE than CG.
Ronaldo C Granjeiro; Helga M Kehrle; Roberta L Bezerra; Vanessa F Almeida; André L L Sampaio; Carlos A Oliveira
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery     Volume:  138     ISSN:  0194-5998     ISO Abbreviation:  Otolaryngol Head Neck Surg     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-24     Completed Date:  2008-05-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508176     Medline TA:  Otolaryngol Head Neck Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  502-6     Citation Subset:  IM    
Secretaria de Saúde do Governo do Distrito Federal, Brasília, Brasil.
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MeSH Terms
Case-Control Studies
Hair Cells, Auditory, Outer / physiology
Middle Aged
Otoacoustic Emissions, Spontaneous / physiology*
Tinnitus / physiopathology*

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