Document Detail


Transient changes in blood pressure during spontaneous deep breaths in rats with sinoaortic deafferentation.
MedLine Citation:
PMID:  1568987     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sinoaortic deafferentation (SAD) in rats produces moderate increases in mean arterial pressure (MAP) along with a large augmentation of arterial pressure lability (APL). The mechanisms generating this APL are incompletely understood. To study the possible influence of breathing activity on APL in conscious SAD rats, we simultaneously recorded pulmonary ventilation and arterial blood pressure. The general pattern of pulmonary ventilation was the same in normal, sham-operated, and SAD rats. In all groups single large tidal volumes were regularly interposed in 1- to 2-min periods of shallower breathing. In SAD rats these single large inspirations were consistently accompanied by substantial and abrupt reductions of MAP, whereas this effect was markedly smaller or absent in normal and sham-operated rats. The data reflect the lack of fast moment-to-moment control of arterial pressure normally exerted by the aortic and carotid baroreceptors. In this context, effects of ventilatory changes must be considered along with humoral and neurogenic factors to explain APL after SAD.
Authors:
B H Machado; H Mauad; M L Glass
Related Documents :
19633447 - Effect of rhythmic melatonin administration on clock gene expression in the suprachiasm...
19646497 - Bolus intravenous injection of obestatin does not change blood pressure level of sponta...
8411637 - In vivo profile of myocardial energy metabolism of pressure-overloaded rat.
24222387 - Magnetocaloric effect and critical behaviour in mn2-pyridazine-[nb(cn)8] molecular comp...
3717257 - A new approach to stratified normal intraocular pressure in a general population.
19633447 - Effect of rhythmic melatonin administration on clock gene expression in the suprachiasm...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  72     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-05-27     Completed Date:  1992-05-27     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  920-4     Citation Subset:  IM    
Affiliation:
Department of Physiology, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure / physiology*
Denervation
Hemodynamics / physiology
Male
Pressoreceptors / physiology
Rats
Rats, Inbred Strains
Respiratory Mechanics / physiology*
Sinoatrial Node / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of acute exercise intensity on plasma lipids and apolipoproteins in trained runners.
Next Document:  Mechanisms of control of alae nasi muscle activity.