Document Detail


Transient changes on brain magnetic resonance imaging in a patient with sturge-weber syndrome presenting with hemiparesis.
MedLine Citation:
PMID:  19901718     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Stroke-like episodes associated with Sturge-Weber Syndrome have previously been attributed to thrombosis within the leptomeningeal malformation causing infarction. CASE REPORT: A 22-year-old woman with a right-sided port-wine nevus presented with acute left hemiparesis. Brain magnetic resonance imaging (MRI) demonstrated a vascular malformation of the right cerebral hemisphere consistent with Sturge-Weber Syndrome. There was mild edema of the right hemisphere cortex. While in hospital she developed recurrent complex partial seizures. Repeat brain MRI showed a diffusion abnormality affecting the right hemisphere with an increase in the degree of edema. There was no evidence of thrombosis on cerebral angiography. The patient's neurologic deficit and acute MRI changes subsequently resolved. CONCLUSIONS: Although cerebral angiography could potentially demonstrate thrombosis causing large vessel obstruction, it is unlikely to have the resolution to detect stasis at a microvascular level. Microcirculatory stasis with reversible ischemia is the likely pathogenic mechanism in this case.
Authors:
Kishore R Kumar; Kenneth Hon; David Schultz; Mark J Agzarian; David Neil Jones; Dominic Thyagarajan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The neurologist     Volume:  15     ISSN:  1074-7931     ISO Abbreviation:  Neurologist     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-10     Completed Date:  2010-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9503763     Medline TA:  Neurologist     Country:  United States    
Other Details:
Languages:  eng     Pagination:  351-4     Citation Subset:  IM    
Affiliation:
Royal Adelaide Hospital, Adelaide, South Australia, Australia. kkumaradel@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Brain / pathology*,  radionuclide imaging
Female
Humans
Magnetic Resonance Angiography / methods
Magnetic Resonance Imaging / methods*
Paresis / complications*,  pathology*,  radionuclide imaging
Positron-Emission Tomography / methods
Sturge-Weber Syndrome / complications*,  pathology*,  radionuclide imaging
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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