Document Detail


Transient atriovenous reconnection induced by adenosine after successful pulmonary vein isolation with the cryothermal energy balloon.
MedLine Citation:
PMID:  19880852     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: Cryothermal energy balloon ablation (CBA), using cryogenic ablative energy, has proven very effective in producing pulmonary vein (PV) isolation in patients with paroxysmal atrial fibrillation (AF). Adenosine testing after PV isolation has demonstrated to be able to unmask incomplete lesion after radiofrequency (RF) ablation. The aim of our study was to assess the rate of transient atriovenous reconnection induced by adenosine after successful PV isolation with the CBA in a group of patients with paroxysmal AF. METHODS AND RESULTS: We prospectively enrolled 39 patients (31 male; age 59 +/- 11 years) elected to circumferential PV isolation with CBA for highly symptomatic paroxysmal AF. A total of 149 PVs were evidenced. Adenosine testing after CBA induced a left atrium-PV reconnection only in 7 (4.6%) of PV. CONCLUSION: Our study showed a low rate of transient PV reconnection after adenosine infusion following successful PV isolation with CBA. However, larger studies will be needed in order to confirm our findings and the prognostic value of adenosine testing after successful PV isolation obtained with CBA.
Authors:
Gian Battista Chierchia; Yoshinao Yazaki; Antonio Sorgente; Lucio Capulzini; Carlo de Asmundis; Andrea Sarkozy; Matthias Duytschaever; Roberto De Ponti; Pedro Brugada
Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2009-10-31
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  11     ISSN:  1532-2092     ISO Abbreviation:  Europace     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-25     Completed Date:  2010-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  1606-11     Citation Subset:  IM    
Affiliation:
Heart Rhythm Management Centre, UZ Brussel-VUB, Laarbeeklaan 101, Brussels, Belgium. gbchier@yahoo.it
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MeSH Terms
Descriptor/Qualifier:
Adenosine / diagnostic use*
Anti-Arrhythmia Agents / diagnostic use
Atrial Fibrillation / diagnosis*,  surgery*
Atrioventricular Node / drug effects
Catheter Ablation / methods*
Cryosurgery / methods*
Electrocardiography / drug effects*
Female
Heart Conduction System / surgery*
Humans
Male
Middle Aged
Prognosis
Pulmonary Veins / surgery*
Reproducibility of Results
Sensitivity and Specificity
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 58-61-7/Adenosine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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