| Transient IgA nephropathy with acute kidney injury in a patient with dengue fever. | |
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MedLine Citation:
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PMID: 20427882 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Dengue virus infection can clinically manifest as dengue fever, dengue shock syndrome and dengue hemorrhagic fever. Acute kidney injury as a result of dengue virus infection can occur due to various reasons including hypotension, rhabdomyolysis, sepsis and rarely immune complex mediated glomerular injury. However, glomerulonephritis associated with IgA Nephropathy in dengue virus infection has not been reported previously. We report a case of 15-year-old boy who was admitted with dengue fever and dialysis dependant acute kidney injury. Urine examination showed microscopic glomerular hematuria and proteinuria. Kidney biopsy showed mesangial proliferation with mesangial IgA dominant immune complex deposits and acute tubular necrosis. A repeated kidney biopsy 6 weeks after clinical recovery showed reversal of glomerular changes as well as resolution of mesangial IgA deposits. |
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Authors:
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Bala Krishna Upadhaya; Alok Sharma; Ambar Khaira; Amit K Dinda; Sanjay K Agarwal; Suresh C Tiwari |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia Volume: 21 ISSN: 1319-2442 ISO Abbreviation: Saudi J Kidney Dis Transpl Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-07-19 Completed Date: 2010-08-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9436968 Medline TA: Saudi J Kidney Dis Transpl Country: Saudi Arabia |
Other Details:
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Languages: eng Pagination: 521-5 Citation Subset: IM |
Affiliation:
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Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adolescent Anti-Infective Agents / therapeutic use Biopsy Dengue / complications*, diagnosis, immunology, therapy Fluorescent Antibody Technique Glomerulonephritis, IGA / diagnosis, immunology, therapy, virology* Glomerulonephritis, Membranoproliferative / diagnosis, immunology, therapy, virology* Hematuria / virology Humans Kidney Cortex Necrosis / diagnosis, immunology, therapy, virology* Kidney Glomerulus / pathology Male Proteinuria / virology Renal Dialysis Treatment Outcome Urine / chemistry, cytology |
| Chemical | |
Reg. No./Substance:
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0/Anti-Infective Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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