| Transient cardiac ballooning--the syndrome. | |
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MedLine Citation:
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PMID: 19938049 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Transient cardiac ballooning is usually a reversible clinical entity. A patient typically presents with chest pain, electrocardiogram (ECG) abnormalities like ST-segment elevation (most commonly reported) or depression, and elevated cardiac enzymes, but has no or nonobstructive coronary artery disease. Left ventriculography reveals transient akinesis of the involved portion of the myocardial wall with compensatory hyperkinesis of the remaining myocardium, leading to ballooning of the noncontracting myocardial wall during systole. Acute regional myocardial dysfunction ensues, which normalizes on average within 1 to 6 weeks. The hypotheses for these pathophysiologic changes range from direct cardiac myocyte injury to postischemic myocardial stunning to neurotransmitter actions. The objective of this article is to present a succinct description of a small case series accompanied with various recently reported presentations and morphology by left ventriculogram and a detailed review of available data on underlying pathophysiology. In addition, a discussion on current diagnostic guidelines, treatment, prognosis, and potential future investigations is included. |
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Authors:
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Raghav Gupta; Candice Sech; Ralph Lazzara |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Clinical cardiology Volume: 32 ISSN: 1932-8737 ISO Abbreviation: Clin Cardiol Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-11-30 Completed Date: 2010-02-04 Revised Date: 2010-04-15 |
Medline Journal Info:
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Nlm Unique ID: 7903272 Medline TA: Clin Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 614-20 Citation Subset: IM |
Affiliation:
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Section of Cardiovascular Diseases, Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA. raghav-gupta@ouhsc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angina Pectoris / etiology Biological Markers / blood Cardiovascular Agents / therapeutic use Coronary Angiography Electrocardiography Female Heart Ventricles* / enzymology, pathology, physiopathology Humans Middle Aged Myocardium / enzymology, pathology Practice Guidelines as Topic Stress, Psychological / complications Stroke Volume Takotsubo Cardiomyopathy* / diagnosis, drug therapy, etiology, physiopathology Treatment Outcome Up-Regulation Ventricular Function, Left |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Cardiovascular Agents |
| Comments/Corrections | |
Comment In:
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Clin Cardiol. 2010 Apr;33(4):241-2; author reply 242
[PMID:
20394045
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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