Document Detail


Transfusional hemosiderosis in sickle cell anemia: another cause of an echogenic pancreas.
MedLine Citation:
PMID:  8516039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report four sickle cell anemia patients who have received multiple blood transfusions and have been non-compliant on Desferal chelation therapy. Abdominal ultrasonography demonstrated an echogenic pancreas in all four patients. Magnetic resonance imaging in three patients revealed decreased signal intensity in all sequences in the pancreas and liver. All four patients had marked iron deposition on liver biopsy. To our knowledge, increased echogenicity of the pancreas secondary to hemosiderosis (2 degrees hemochromatosis) in sickle cell patients has not been reported in the radiologic literature.
Authors:
M A Flyer; J O Haller; R Sundaram
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric radiology     Volume:  23     ISSN:  0301-0449     ISO Abbreviation:  Pediatr Radiol     Publication Date:  1993  
Date Detail:
Created Date:  1993-07-22     Completed Date:  1993-07-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  140-2     Citation Subset:  IM    
Affiliation:
Department of Radiology, State University of New York, Health Science Center, Brooklyn 11203.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Anemia, Sickle Cell / therapy*
Blood Transfusion / adverse effects*
Child
Child, Preschool
Hemosiderosis / etiology,  metabolism,  ultrasonography*
Humans
Iron / metabolism
Liver / metabolism,  ultrasonography
Pancreas / metabolism,  ultrasonography*
Chemical
Reg. No./Substance:
7439-89-6/Iron

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