Document Detail

Transfusion-related acute lung injury in the paediatric patient: Two case reports and a review of the literature.
MedLine Citation:
PMID:  16999757     Owner:  NLM     Status:  MEDLINE    
Transfusion-related acute lung injury (TRALI) is increasingly recognized as a major complication of transfusion therapy; it was the leading cause of transfusion-related fatalities in the United States in 2003. Most cases of TRALI that have been reported are in adult patients. We present two cases of TRALI that occurred in children and review the existing literature of paediatric TRALI. The paediatric TRALI case reports highlight two laboratory findings that can help in the diagnosis of TRALI: transient leucopenia and an elevated pulmonary oedema fluid/plasma protein ratio. These two simple diagnostic tests can help rule out other diagnoses and add confidence to the clinical diagnosis of TRALI. Finally, our first case also highlights the potential danger of directed maternal blood donations, which may increase the risk of paediatric TRALI.
G D Church; C Price; R Sanchez; M R Looney
Related Documents :
16525197 - An outbreak of airborne tularaemia in france, august 2004.
20663117 - Disseminated mycobacterium genavense with pulmonary nodules in a kidney transplant reci...
2103317 - Multiple, relapsing thrombosis in a young man with primary thrombocytosis.
12675767 - Pulmonary lymphangioleiomyomatosis and multiple hepatic angiomyolipomas in a man.
6497237 - An unusual form of laryngeal paralysis associated with arnold-chiari malformation.
3962177 - Intestinal atresia and stenosis: a review comparing its etiopathogenesis.
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Transfusion medicine (Oxford, England)     Volume:  16     ISSN:  0958-7578     ISO Abbreviation:  Transfus Med     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-26     Completed Date:  2006-11-07     Revised Date:  2008-07-31    
Medline Journal Info:
Nlm Unique ID:  9301182     Medline TA:  Transfus Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  343-8     Citation Subset:  IM    
Cardiovascular Research Institute, Department of Pediatrics, University of California, San Francisco, San Francisco, California 94143-0130, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Donors
Blood Proteins / analysis
Blood Transfusion / adverse effects*
Histocompatibility / immunology
Histocompatibility Testing / methods
Leukopenia / etiology
Pulmonary Edema / etiology
Respiratory Distress Syndrome, Adult / complications,  diagnosis,  etiology*
Reg. No./Substance:
0/Blood Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Perioperative intravenous iron preserves iron stores and may hasten the recovery from post-operative...
Next Document:  Diagnosis of acute foetal distress does not preclude banking of umbilical cord blood units.