Document Detail

Transfusion practice in hip arthroplasty - a nationwide study.
MedLine Citation:
PMID:  21029109     Owner:  NLM     Status:  In-Data-Review    
Background and Objectives  The optimal transfusion strategy in hip arthroplasty remains controversial despite existing guidelines. The aim of this study was to evaluate the transfusion practice in patients undergoing primary total hip arthroplasty (THA) or revision total hip arthroplasty (RTHA) in Denmark. Materials and Methods  We performed a retrospective cohort study of all patients undergoing THA or RTHA in Denmark in 2008. Primary outcomes were intercentre variation in red blood cell (RBC) transfusion rates and the timing of transfusion related to surgery. Results  Six thousand nine hundred thirty-two THA patients and 1132 RTHA patients were included for analysis of which 1674 (24%) THA and 689 (61%) RTHA patients received RBC transfusion. Of these, 47% of THA and 73% of RTHA patients received transfusion on the day of surgery. Transfusion rates between centres varied from 7 to 71% and between 26 and 85% in THA and RTHA patients, respectively. Patients receiving RBC transfusion had longer length of stay and for THA patients an increased odds-ratio (5·5) of death within 90 days. Conclusion  Despite established guidelines, RBC transfusion practice in hip arthroplasty remains highly variable between Danish hospitals. The effect of RBC transfusion on outcome after hip arthroplasty should be established in prospective randomized controlled trials.
O Jans; H Kehlet; Z Hussain; P I Johansson
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Publication Detail:
Type:  Journal Article     Date:  2010-10-28
Journal Detail:
Title:  Vox sanguinis     Volume:  100     ISSN:  1423-0410     ISO Abbreviation:  Vox Sang.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413606     Medline TA:  Vox Sang     Country:  England    
Other Details:
Languages:  eng     Pagination:  374-80     Citation Subset:  IM    
Copyright Information:
© 2010 The Author(s). Vox Sanguinis © 2010 International Society of Blood Transfusion.
Section of Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark Lundbeck Centre for Fast-track Hip and Knee Arthroplasty, Copenhagen, Denmark National Board of Health, Monitoring & Health Technology Assessment, Copenhagen, Denmark Capital Region Blood Bank, Rigshospitalet, Copenhagen, Denmark.
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