Document Detail

Transfusion practice in elective orthopaedic surgery.
MedLine Citation:
PMID:  11299025     Owner:  NLM     Status:  MEDLINE    
. The transfusion requirements of 2233 patients who underwent total hip or knee joint arthroplasty procedures at nine Canadian hospitals during 1995-1996 were evaluated. Although 64% of patients were eligible for participation in an autologous blood donation (ABD) programme, only 8% predonated blood. Patients who were eligible for ABD were younger (62 years vs. 70 years) and had fewer medical illnesses (18% vs. 44%) than those who did not predonate. The rate of allogeneic transfusion was 9.0% (95% confidence interval 4.9-13.1%) in patients who predonated as compared with 24.1% (95% confidence interval 22.2-25.9%) in those who did not. Risk factors for the occurrence of an allogeneic transfusion were type of procedure (primary or revision hip arthroplasty), lower baseline haemoglobin, lower body weight, older age and presence of rheumatoid arthritis (P < 0.001). Only patients without risk factors were predicted to have a less than 10% risk of receiving an allogeneic transfusion. Use of preventive strategies was minimal. Two models designed to predict the occurrence of an allogeneic transfusion were evaluated. If allogeneic transfusion rates are to be reduced, eligible patients should be encouraged to participate in ABD programmes. For patients who are ineligible, other preventative strategies should be introduced.
B G Feagan; C J Wong; C Y Lau; S L Wheeler; G Sue-A-Quan; A Kirkley
Related Documents :
1586705 - Interferon-gamma gene expression in unstimulated bone marrow mononuclear cells predicts...
3538535 - Marrow graft rejection and veno-occlusive disease of the liver in patients with aplasti...
9371095 - Plasmodium falciparum: evaluation of lactate dehydrogenase in monitoring therapeutic re...
7577635 - Splenic irradiation for chronic autoimmune thrombocytopenic purpura in patients with co...
7660215 - Eosinophilia-myalgia syndrome: a long-term follow-up study.
20150385 - A phase i/ii trial of enzastaurin in patients with recurrent high-grade gliomas.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transfusion medicine (Oxford, England)     Volume:  11     ISSN:  0958-7578     ISO Abbreviation:  Transfus Med     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-04-12     Completed Date:  2001-10-11     Revised Date:  2008-07-31    
Medline Journal Info:
Nlm Unique ID:  9301182     Medline TA:  Transfus Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  87-95     Citation Subset:  IM    
London Clinical Trials Research Group, The John P. Robarts Research Institute, London, Ontario, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Analysis of Variance
Arthroplasty, Replacement, Hip
Blood Transfusion / standards,  utilization*
Blood Transfusion, Autologous / utilization
Decision Support Techniques
Middle Aged
Orthopedic Procedures*
Retrospective Studies
Risk Factors
Surgical Procedures, Elective*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Utilization of technologies to reduce allogeneic blood transfusion in the United States.
Next Document:  Endogenous glutathione and platelet function in platelet concentrates stored in plasma or platelet a...