| Transfusion in the critically ill: does it affect outcome? | |
| | |
MedLine Citation:
|
PMID: 20827065 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Anemia and red blood cell (RBC) transfusions are common in critically ill and injured, trauma, and surgical patients. Tolerance of anemia is highly variable, depending on the presence of cardiovascular and other comorbid diseases that may diminish the hemodynamic response to a lower hemoglobin (Hb) level. The quest to define a minimum threshold Hb concentration at which patients achieve significant benefit to improve outcome has not yet been identified. Complications related to RBC transfusion are related to RBC storage and intrinsic properties of donor allogeneic RBCs, including bacterial contamination, transfusion-related acute lung injury, and transfusion-related immunomodulation. The best evidence related to transfusion-related outcome involves titrating transfusion requirements to parameters of severity of illness rather than arbitrarily defined Hb levels. |
| | |
Authors:
|
M Roseann Cannon-Diehl |
Related Documents
:
|
11455745 - Anaemia in the critically ill--the optimal haematocrit. 17572415 - Massive blood transfusion and trauma resuscitation. 15838215 - Blood-conservation techniques in craniofacial surgery. 3383975 - Effect of perioperative blood loss and perioperative blood transfusions on colorectal c... 17406115 - Duplex scanning diagnosis of internal carotid artery dissections. a case control study. 1889065 - Comparison of estimates of cardiac output by indicator dilution and freon 22 uptake dur... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Critical care nursing quarterly Volume: 33 ISSN: 1550-5111 ISO Abbreviation: Crit Care Nurs Q Publication Date: 2010 Oct-Dec |
Date Detail:
|
Created Date: 2010-09-09 Completed Date: 2011-02-01 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8704517 Medline TA: Crit Care Nurs Q Country: United States |
Other Details:
|
Languages: eng Pagination: 324-38 Citation Subset: N |
Affiliation:
|
Department of Anesthesiology, Sanford-MeritCare Healthcare System, MeritCare Hospital, Fargo, North Dakota, USA. roseanncannon@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anemia
/
prevention & control* Blood Transfusion* Critical Care / organization & administration* Humans Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: High-tech/high-touch team-centered care provides best outcomes for wound prevention in critically il...
Next Document: Ventilator-associated pneumonia: the importance of oral care in intubated adults.