| Transfusion of blood and blood products: indications and complications. | |
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MedLine Citation:
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PMID: 21404983 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Red blood cell transfusions are used to treat hemorrhage and to improve oxygen delivery to tissues. Transfusion of red blood cells should be based on the patient's clinical condition. Indications for transfusion include symptomatic anemia (causing shortness of breath, dizziness, congestive heart failure, and decreased exercise tolerance), acute sickle cell crisis, and acute blood loss of more than 30 percent of blood volume. Fresh frozen plasma infusion can be used for reversal of anticoagulant effects. Platelet transfusion is indicated to prevent hemorrhage in patients with thrombocytopenia or platelet function defects. Cryoprecipitate is used in cases of hypofibrinogenemia, which most often occurs in the setting of massive hemorrhage or consumptive coagulopathy. Transfusion-related infections are less common than noninfectious complications. All noninfectious complications of transfusion are classified as noninfectious serious hazards of transfusion. Acute complications occur within minutes to 24 hours of the transfusion, whereas delayed complications may develop days, months, or even years later. |
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Authors:
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Sanjeev Sharma; Poonam Sharma; Lisa N Tyler |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American family physician Volume: 83 ISSN: 1532-0650 ISO Abbreviation: Am Fam Physician Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1272646 Medline TA: Am Fam Physician Country: United States |
Other Details:
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Languages: eng Pagination: 719-24 Citation Subset: AIM; IM |
Affiliation:
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Creighton University School of Medicine, Omaha, NE, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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